B3gnt8 Gene Summary [Rat]

Enables protein N-acetylglucosaminyltransferase activity. Involved in poly-N-acetyllactosamine biosynthetic process. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
B3gnt8
Official Name
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8 [Source:RGD Symbol;Acc:1305374]
Ensembl ID
ENSRNOG00000020606
Bio databases IDs NCBI: 308440 Ensembl: ENSRNOG00000020606
Aliases UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8
Synonyms B3GALT7, B7galt7, beta3Gn-T8, BGALT15, UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8, UDP-GlcNAc:betaGal β-1,3-N-acetylglucosaminyltransferase 8
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat B3gnt8 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • UDP-galactose beta-N-acetylglucosamine beta-1,3-galactosyltransferase
  • galactosyltransferase
  • enzyme
  • protein binding
  • protein N-acetylglucosaminyltransferase

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • androgenic alopecia
regulated by
  • SOX4
  • dimethyl sulfoxide
regulates
  • B3GNT2
  • O-glycan
  • poly-N-acetyllactosamine

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Golgi membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat B3gnt8 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • protein O-linked glycosylation
  • O-glycan processing
  • poly-N-acetyllactosamine biosynthetic process

Cellular Component

Where in the cell the gene product is active
  • extracellular vesicular exosome
  • Golgi membrane

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • protein N-acetylglucosaminyltransferase activity
  • UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.