CASC2 Gene Summary [Human]
Involved in defense response to tumor cell; negative regulation of MAPK cascade; and positive regulation of cysteine-type endopeptidase activity involved in apoptotic process. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Long Non-Coding RNA |
| Official Symbol | CASC2 |
| Official Name | cancer susceptibility 2 [Source:HGNC Symbol;Acc:HGNC:22933] |
| Ensembl ID | ENSG00000177640 |
| Bio databases IDs | |
| Aliases | cancer susceptibility 2 |
| Synonyms | C10orf5, cancer susceptibility 2 |
| Species | Human, Homo sapiens |
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- endometrial carcinoma
- epithelial endometrial cancer
- colorectal cancer
- endometrial cancer
- colorectal neoplasm
- colorectal neoplasia
- gastric carcinoma
- gastric epithelial cancer
- ptosis
- chronic obstructive pulmonary disease
role in cell
- growth
- expression in
- mineralization
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human CASC2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
- defense response to tumor cell
- negative regulation of MAPK cascade