SPIN3 Gene Summary [Human]

Enables methylated histone binding activity. Predicted to be involved in regulation of transcription, DNA-templated. Predicted to be integral component of membrane. Predicted to be active in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Nonsense Mediated Decay
Official Symbol
SPIN3
Official Name
spindlin family member 3 [Source:HGNC Symbol;Acc:HGNC:27272]
Ensembl ID
ENSG00000204271
Bio databases IDs NCBI: 169981 Ensembl: ENSG00000204271
Aliases spindlin family member 3
Synonyms bA445O16.1, spindlin family member 3, TDRD27
Species
Human, Homo sapiens

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human SPIN3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Spin/Ssty Family
  • protein binding activity, bridging
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • systemic lupus erythematosus
  • hepatitis B
  • neuroticism

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Unknown

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human SPIN3 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • regulation of transcription, DNA-dependent
  • gamete generation

Cellular Component

Where in the cell the gene product is active
  • cytosol
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • methylated histone residue binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.