TCHHL1 Gene Summary [Human]
This gene belongs to the S100 fused-type protein (SFTP) gene family, and is located in a cluster of SFTP genes on chromosome 1q21. Several members of this family have been implicated in the development of complex skin disorders. This gene is evolutionarily conserved; its expression appears to be hair-specific and spatially restricted within the distal inner root sheath of the hair follicle. It thus may have an important role in hair morphogenesis. [provided by RefSeq, Aug 2013]
Details
| Type | Protein Coding |
| Official Symbol | TCHHL1 |
| Official Name | trichohyalin like 1 [Source:HGNC Symbol;Acc:HGNC:31796] |
| Ensembl ID | ENSG00000182898 |
| Bio databases IDs | |
| Aliases | trichohyalin like 1 |
| Synonyms | 5430400H23Rik, RGD1308305, S100A17, THHL1, trichohyalin-like 1 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human TCHHL1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- S-100/ICaBP type calcium binding domain
- EFh
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human TCHHL1 gene, providing context for its role in the cell.
Molecular Function
What the gene product does at the molecular level
- transition metal ion binding