PFN3 Gene Summary [Human]
The product of this gene belongs to the profilin family of proteins. This protein binds to actin and affects the structure of the cytoskeleton. It also may be involved in spermatogenesis. It is a single exon gene. [provided by RefSeq, Jul 2008]
Details
| Type | Protein Coding |
| Official Symbol | PFN3 |
| Official Name | profilin 3 [Source:HGNC Symbol;Acc:HGNC:18627] |
| Ensembl ID | ENSG00000196570 |
| Bio databases IDs | |
| Aliases | profilin 3 |
| Synonyms | 1700012P12Rik, LOC684227, profilin-3 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human PFN3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- PROF
- actin binding
- Profilin
- protein binding
Pathways
Biological processes and signaling networks where the PFN3 gene in human plays a role, providing insight into its function and relevance in health or disease.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human PFN3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of actin filament polymerization
- positive regulation of actin filament bundle assembly
- actin cytoskeleton organization
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytoskeleton
- cytoplasm
Molecular Function
What the gene product does at the molecular level
- actin binding
- lipid binding