ARHGEF37 Gene Summary [Human]
Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in regulation of catalytic activity. Predicted to be located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | ARHGEF37 |
| Official Name | Rho guanine nucleotide exchange factor 37 [Source:HGNC Symbol;Acc:HGNC:34430] |
| Ensembl ID | ENSG00000183111 |
| Bio databases IDs | |
| Aliases | Rho guanine nucleotide exchange factor 37 |
| Synonyms | 4933429F08Rik, RGD1560471, Rho guanine nucleotide exchange factor 37 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human ARHGEF37 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- RhoGEF
- Bacterial SH3 domain
- BAR domain
- Bin/Amphiphysin/Rvs domain
- RhoGEF domain
- Src Homology 3 domain superfamily
Pathways
Biological processes and signaling networks where the ARHGEF37 gene in human plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human ARHGEF37 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- cytoplasm
Molecular Function
What the gene product does at the molecular level
- guanyl-nucleotide exchange factor activity