SNN Gene Summary [Human]

Enables metal ion binding activity. Predicted to be involved in response to toxic substance. Located in cytoplasm. Is integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
SNN
Official Name
stannin [Source:HGNC Symbol;Acc:HGNC:11149]
Ensembl ID
ENSG00000184602
Bio databases IDs NCBI: 8303 Ensembl: ENSG00000184602
Aliases stannin
Synonyms 2810407J07Rik, Stannin
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human SNN often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Stannin transmembrane
  • Stannin unstructured linker
  • metal ion binding
  • Stannin cytoplasmic
  • Stannin family includes vertebrate Stannin and insect Hemotin

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • severe acute respiratory syndrome
regulated by
  • HTT
  • TNF
  • beta-estradiol
  • AIRE
  • IgG
  • ESR1
  • methylprednisolone
  • megakaryocytes
  • SOS
  • Wy 40905
role in cell
  • cell death

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane
  • membrane fraction
  • Cytoplasm
  • cellular membrane
  • Mitochondria
  • endosomes and endoplasmic reticulum fractions
  • cytosolic fraction

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human SNN gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • response to toxin

Cellular Component

Where in the cell the gene product is active
  • cytoplasm
  • membrane
  • mitochondrial outer membrane

Molecular Function

What the gene product does at the molecular level
  • metal ion binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.