RBM11 Gene Summary [Human]

Enables poly(U) RNA binding activity and protein homodimerization activity. Acts upstream of or within cellular response to oxidative stress and regulation of alternative mRNA splicing, via spliceosome. Located in nuclear speck. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Processed Transcript
Official Symbol
RBM11
Official Name
RNA binding motif protein 11 [Source:HGNC Symbol;Acc:HGNC:9897]
Ensembl ID
ENSG00000185272
Bio databases IDs NCBI: 54033 Ensembl: ENSG00000185272
Aliases RNA binding motif protein 11
Synonyms A330018F01, RNA binding motif protein 11
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human RBM11 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • RNA recognition motif (RRM) superfamily
  • RNA recognition motif
  • protein homodimerization
  • protein binding
  • poly(U) binding protein

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
role in cell
  • alternative splicing by
  • response by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • nucleoplasm
  • nuclear speckles

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human RBM11 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • RNA splicing
  • regulation of alternative nuclear mRNA splicing, via spliceosome
  • cell differentiation
  • cellular response to oxidative stress
  • mRNA processing

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • nuclear speck
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • protein homodimerization activity
  • protein binding
  • single-stranded RNA binding
  • poly(U) RNA binding

Gene-Specific Assays for Results You Can Trust

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