GPAT2 Gene Summary [Human]
Enables glycerol-3-phosphate O-acyltransferase activity. Predicted to be involved in several processes, including glycerol-3-phosphate metabolic process; glycerolipid biosynthetic process; and piRNA biosynthetic process. Predicted to be located in mitochondrial outer membrane. Predicted to be active in mitochondrial membrane. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Retained Intron |
| Official Symbol | GPAT2 |
| Official Name | glycerol-3-phosphate acyltransferase 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:27168] |
| Ensembl ID | ENSG00000186281 |
| Bio databases IDs | |
| Aliases | glycerol-3-phosphate acyltransferase 2, mitochondrial, cancer/testis antigen 123 |
| Synonyms | A530057A03Rik, CT123, glycerol-3-phosphate acyltransferase 2, mitochondrial, Gm116, RGD1304904, xGPAT1 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human GPAT2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis
- 1-acylglycerol-3-phosphate O-acyltransferase
- glycerol-3-phosphate O-acyltransferase
- enzyme
- protein binding
- Acyltransferase
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria
- mitochondrial outer membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human GPAT2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- glycerol-3-phosphate metabolic process
- phospholipid biosynthetic process
- triglyceride biosynthetic process
- piRNA metabolic process
- CDP-diacylglycerol biosynthetic process
- fatty acid metabolic process
- phosphatidic acid biosynthetic process
Cellular Component
Where in the cell the gene product is active
- mitochondrial membrane
- mitochondrion
- mitochondrial outer membrane
Molecular Function
What the gene product does at the molecular level
- 1-acylglycerol-3-phosphate O-acyltransferase activity
- glycerol-3-phosphate O-acyltransferase activity