RNF133 Gene Summary [Human]
The protein encoded by this gene contains a RING finger domain, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions. This gene has no intron. [provided by RefSeq, Jul 2008]
Details
| Type | Protein Coding |
| Official Symbol | RNF133 |
| Official Name | ring finger protein 133 [Source:HGNC Symbol;Acc:HGNC:21154] |
| Ensembl ID | ENSG00000188050 |
| Bio databases IDs | |
| Aliases | ring finger protein 133 |
| Synonyms | Greul2, LOC681784, ring finger protein 133 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human RNF133 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- PA domain
- PA
- RING finger (Really Interesting New Gene) domain and U-box domain superfamily
- Ring finger
- Ring finger domain
- RING-like zinc finger
- RING-H2 zinc finger domain
- Zinc finger, C3HC4 type (RING finger)
- zinc-RING finger domain
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- endoplasmic reticulum membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human RNF133 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- protein autoubiquitination
- ubiquitin-dependent protein catabolic process
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum membrane
- cytoplasm
- late endosome
- endoplasmic reticulum
- Golgi apparatus
Molecular Function
What the gene product does at the molecular level
- metal ion binding