SBK1 Gene Summary [Human]
Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in peptidyl-serine phosphorylation and peptidyl-threonine phosphorylation. Predicted to be located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | SBK1 |
| Official Name | SH3 domain binding kinase 1 [Source:HGNC Symbol;Acc:HGNC:17699] |
| Ensembl ID | ENSG00000188322 |
| Bio databases IDs | |
| Aliases | SH3 domain binding kinase 1 |
| Synonyms | LOC103690016, LOC112868, SBK, SH3-binding domain kinase 1, SH3-binding kinase 1, SH3 domain binding kinase 1 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human SBK1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- kinase
- Serine/Threonine protein kinases, catalytic domain
- protein serine/threonine kinase
- Protein kinase (unclassified specificity)
- Protein Kinases, catalytic domain
- Protein tyrosine and serine/threonine kinase
- Protein kinase domain
- Tyrosine kinase, catalytic domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- systemic lupus erythematosus
- metabolic syndrome X
- pervasive developmental disorder
- lung adenocarcinoma
- lung adenocarcinoma formation
- acute myeloid leukemia
- inflammatory bowel disease
- allergy
regulates
- peptide
- L-threonine
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human SBK1 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- cytoplasm
Molecular Function
What the gene product does at the molecular level
- ATP binding
- protein serine/threonine kinase activity