ZDHHC11 Gene Summary [Human]
Enables signaling adaptor activity. Involved in antiviral innate immune response and positive regulation of defense response to virus by host. Located in endoplasmic reticulum. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Processed Transcript |
| Official Symbol | ZDHHC11 |
| Official Name | zinc finger DHHC-type containing 11 [Source:HGNC Symbol;Acc:HGNC:19158] |
| Ensembl ID | ENSG00000188818 |
| Bio databases IDs | |
| Aliases | zinc finger DHHC-type containing 11 |
| Synonyms | zinc finger DHHC-type containing 11, ZNF399 |
| Species | Human, Homo sapiens |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human ZDHHC11 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding activity, bridging
- protein-cysteine S-palmitoleyltransferase
- DHHC palmitoyltransferase
- enzyme
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- cellular membrane
- Endoplasmic Reticulum
- Golgi membrane
- endosomal membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human ZDHHC11 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- peptidyl-L-cysteine S-palmitoylation
- positive regulation of defense response to virus by host
- protein targeting to membrane
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum membrane
- endosome membrane
- endoplasmic reticulum
- Golgi membrane
- Golgi apparatus
Molecular Function
What the gene product does at the molecular level
- protein-cysteine S-palmitoleyltransferase activity
- protein binding
- signaling adaptor activity