EEF1AKMT2 Gene Summary [Human]
Enables protein-lysine N-methyltransferase activity. Involved in peptidyl-lysine methylation. Located in cytosol and nuclear body. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Nonsense Mediated Decay |
| Official Symbol | EEF1AKMT2 |
| Official Name | EEF1A lysine methyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:33787] |
| Ensembl ID | ENSG00000203791 |
| Bio databases IDs | |
| Aliases | EEF1A lysine methyltransferase 2, eukaryotic translation elongation factor 1 alpha lysine methyltransferase 2 |
| Synonyms | 2010208K18Rik, C10orf138, EEF1A lysine methyltransferase 2, Efm4, FLJ12292, METTL10, RGD1306300 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human EEF1AKMT2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein-lysine N-methyltransferase
- methyltransferase
- enzyme
- AdoMet_MTases
- methyltransferase domain
Pathways
Biological processes and signaling networks where the EEF1AKMT2 gene in human plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Nucleus
- cytosol
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human EEF1AKMT2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- chromatin remodeling
- peptidyl-lysine methylation
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytoplasm
- cytosol
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- histone methyltransferase activity
- methyltransferase activity
- protein-lysine N-methyltransferase activity