TIMM23B
TIMM23B Gene Summary
Predicted to enable protein transmembrane transporter activity. Predicted to be involved in protein import into mitochondrial matrix. Predicted to be part of TIM23 mitochondrial import inner membrane translocase complex. Predicted to be integral component of mitochondrial inner membrane. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Nonsense Mediated Decay |
| Official Symbol | TIMM23B |
| Official Name | translocase of inner mitochondrial membrane 23 homolog B [Source:HGNC Symbol;Acc:HGNC:23581] |
| Ensembl ID | ENSG00000204152 |
| Bio databases IDs | |
| Aliases | translocase of inner mitochondrial membrane 23 homolog B |
| Synonyms | LOC10431,TIM23,translocase of inner mitochondrial membrane 23 homolog B |
| Species | Human, Homo sapiens |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- TIM22
- Tim17/Tim22/Tim23/Pmp24 family
Pathways
Biological processes and signaling networks where the TIMM23B gene plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
- ESR2
- BCAR1
- OFD1
- TOMM40
- APP
- PLEKHA4
- TOP3B
- MCM2
- SQSTM1
- CREB3
disease
- Waldenström macroglobulinemia
regulated by
- TIMM13
- TIMM8A
- NOX4
- VEGFA
regulates
role in cell
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- mitochondrial fraction
- pH resistant lipid raft fraction
- inner membrane
- Mitochondria
- Golgi cisternae rim
- mitochondrial membrane
- mitochondrial inner membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the TIMM23B gene, providing context for its role in the cell.
BIOLOGICAL PROCESS
Functions and activities the gene product is involved in
- protein import into mitochondrial matrix
CELLULAR COMPONENT
Where in the cell the gene product is active
- mitochondrial inner membrane presequence translocase complex
MOLECULAR FUNCTION
What the gene product does at the molecular level
- protein transmembrane transporter activity