CNEP1R1 Gene Summary [Human]
This gene encodes a transmembrane protein that belongs to the Tmemb_18A family. A similar protein in yeast is a component of an endoplasmic reticulum-associated protein phosphatase complex and is thought to play a role in the synthesis of triacylglycerol. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
Details
| Type | Protein Coding |
| Official Symbol | CNEP1R1 |
| Official Name | CTD nuclear envelope phosphatase 1 regulatory subunit 1 [Source:HGNC Symbol;Acc:HGNC:26759] |
| Ensembl ID | ENSG00000205423 |
| Bio databases IDs | |
| Aliases | CTD nuclear envelope phosphatase 1 regulatory subunit 1, nuclear envelope phosphatase 1-regulatory subunit 1 |
| Synonyms | 5033428A16Rik, C16orf69, CTD nuclear envelope phosphatase 1 regulatory subunit 1, NEP1-R1, RGD1308816, TMEM188, TMP125 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human CNEP1R1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein phosphatase regulator
- Transmembrane protein 188
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- Cytoplasm
- cytosol
- endoplasmic reticulum membrane
- nuclear envelope
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human CNEP1R1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- positive regulation of triglyceride biosynthetic process
- lipid metabolic process
- positive regulation of protein dephosphorylation
- protein localization to nucleus
Cellular Component
Where in the cell the gene product is active
- nuclear envelope
- nuclear membrane
- cytoplasm
- Nem1-Spo7 phosphatase complex
- cytosol
Molecular Function
What the gene product does at the molecular level
- protein binding