Cnep1r1 Gene Summary [Mouse]

Predicted to enable protein phosphatase regulator activity. Predicted to be involved in positive regulation of triglyceride biosynthetic process and protein localization to nucleus. Predicted to be located in cytosol and nuclear membrane. Predicted to be part of Nem1-Spo7 phosphatase complex. Predicted to be active in cytoplasm. Orthologous to human CNEP1R1 (CTD nuclear envelope phosphatase 1 regulatory subunit 1). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Cnep1r1
Official Name
CTD nuclear envelope phosphatase 1 regulatory subunit 1 [Source:MGI Symbol;Acc:MGI:1921981]
Ensembl ID
ENSMUSG00000036810
Bio databases IDs NCBI: 382030 Ensembl: ENSMUSG00000036810
Aliases CTD nuclear envelope phosphatase 1 regulatory subunit 1
Synonyms 5033428A16Rik, C16orf69, CTD nuclear envelope phosphatase 1 regulatory subunit 1, NEP1-R1, RGD1308816, TMEM188, TMP125
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Cnep1r1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • protein phosphatase regulator
  • Transmembrane protein 188
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • rheumatoid arthritis
  • diabetes mellitus
  • epithelial cancer
  • kidney carcinoma
  • renal cancer
  • renal clear cell adenocarcinoma
  • renal clear cell cancer
regulates
role in cell
  • quantity
  • production in
  • dephosphorylation in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • Cytoplasm
  • cytosol
  • endoplasmic reticulum membrane
  • nuclear envelope

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Cnep1r1 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • positive regulation of triglyceride biosynthetic process
  • lipid metabolic process
  • positive regulation of protein dephosphorylation
  • protein localization to nucleus

Cellular Component

Where in the cell the gene product is active
  • nuclear envelope
  • nuclear membrane
  • cytoplasm
  • Nem1-Spo7 phosphatase complex
  • cytosol

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.