AMY2B Gene Summary [Human]
Amylases are secreted proteins that hydrolyze 1,4-alpha-glucoside bonds in oligosaccharides and polysaccharides, and thus catalyze the first step in digestion of dietary starch and glycogen. The human genome has a cluster of several amylase genes that are expressed at high levels in either salivary gland or pancreas. This gene encodes an amylase isoenzyme produced by the pancreas. [provided by RefSeq, Jun 2013]
Details
| Type | Nonsense Mediated Decay |
| Official Symbol | AMY2B |
| Official Name | amylase alpha 2B [Source:HGNC Symbol;Acc:HGNC:478] |
| Ensembl ID | ENSG00000240038 |
| Bio databases IDs | |
| Aliases | amylase alpha 2B |
| Synonyms | AMY2, Amy2-2, AMY3, amylase alpha 2B, amylase α 2B, HXA |
| Species | Human, Homo sapiens |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human AMY2B often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Alpha amylase catalytic domain family
- Alpha amylase, catalytic domain
- enzyme
- Alpha amylase, C-terminal all-beta domain
- alpha-amylase
- Maltogenic Amylase, C-terminal domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human AMY2B gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- carbohydrate metabolic process
Cellular Component
Where in the cell the gene product is active
- extracellular space
- extracellular vesicular exosome
Molecular Function
What the gene product does at the molecular level
- alpha-amylase activity
- metal ion binding