EID3 Gene Summary [Human]
Predicted to be involved in DNA repair. Located in nucleolus and nucleoplasm. Part of Smc5-Smc6 complex. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | EID3 |
| Official Name | EP300 interacting inhibitor of differentiation 3 [Source:HGNC Symbol;Acc:HGNC:32961] |
| Ensembl ID | ENSG00000255150 |
| Bio databases IDs | |
| Aliases | EP300 interacting inhibitor of differentiation 3, NSE4 homolog B |
| Synonyms | 1700027M21Rik, EP300 interacting inhibitor of differentiation 3, LOC687496, NS4EB, NSE4B, NSMCE4B |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human EID3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Binding domain of Nse4/EID3 to Nse3-MAGE
- protein binding
- Nse4 C-terminal
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Nucleus
- nucleoplasm
- nucleoli
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human EID3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- DNA repair
- protein sumoylation
- double-strand break repair via homologous recombination
- regulation of telomere maintenance
Cellular Component
Where in the cell the gene product is active
- chromosome, telomeric region
- nucleus
- cytoplasm
- Smc5-Smc6 complex
- nucleolus
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding