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Homeobox genes encode DNA-binding proteins, many of which are thought to be involved in early embryonic development. Homeobox genes encode a DNA-binding domain of 60 to 63 amino acids referred to as the homeodomain. This gene is a member of the DUXA homeobox gene family. Evidence of mRNA expression has not yet been found for this gene. Multiple, related processed pseudogenes have been found which are thought to reflect expression of this gene in the germ line or embryonic cells. [provided by RefSeq, Jul 2008]
Details
Type
Protein Coding
Official Symbol
DUXA
Official Name
double homeobox A [Source:HGNC Symbol;Acc:HGNC:32179]
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human DUXA often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcription regulator
double-stranded DNA binding
sequence-specific DNA binding
homeodomain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
Nucleus
nucleoplasm
chromatin
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human DUXA gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
regulation of transcription from RNA polymerase II promoter
Cellular Component
Where in the cell the gene product is active
nucleus
chromatin
nucleoplasm
Molecular Function
What the gene product does at the molecular level
RNA polymerase II regulatory region sequence-specific DNA binding
sequence-specific DNA binding RNA polymerase II transcription factor activity
Gene-Specific Assays for Results You Can Trust
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