ZNF2 Gene Summary [Human]
The protein encoded by this gene belongs to the C2H2-type zinc-finger protein family. The exact function of this gene is not known, however, zinc-finger proteins are known to interact with DNA and function as transcription regulators. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2014]
Details
| Type | Protein Coding |
| Official Symbol | ZNF2 |
| Official Name | zinc finger protein 2 [Source:HGNC Symbol;Acc:HGNC:12991] |
| Ensembl ID | ENSG00000275111 |
| Bio databases IDs | |
| Aliases | zinc finger protein 2 |
| Synonyms | 2810405K07Rik, A1-5, LOC100909998, LOC102556086, Zfp661, zinc finger protein 2, zinc finger protein 2-like, zinc finger protein 661, ZNF661 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human ZNF2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Zinc finger, C2H2 type
- krueppel associated box
- Zinc-finger double domain
- protein binding
- KRAB (Kruppel-associated box) domain -A box
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human ZNF2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of transcription, DNA-dependent
- regulation of transcription from RNA polymerase II promoter
Cellular Component
Where in the cell the gene product is active
- nucleus
Molecular Function
What the gene product does at the molecular level
- zinc ion binding
- protein binding
- RNA polymerase II core promoter proximal region sequence-specific DNA binding
- sequence-specific DNA binding RNA polymerase II transcription factor activity