TSGA10 Gene Summary [Human]

Predicted to enable structural molecule activity. Predicted to be involved in spermatogenesis. Predicted to act upstream of or within cell projection assembly. Predicted to be located in neuron projection; sperm fibrous sheath; and sperm principal piece. Implicated in spermatogenic failure 26. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
TSGA10
Official Name
testis specific 10 [Source:HGNC Symbol;Acc:HGNC:14927]
Ensembl ID
ENSG00000135951
Bio databases IDs NCBI: 80705 Ensembl: ENSG00000135951
Aliases testis specific 10, cancer/testis antigen 79
Synonyms 4933432N21, 4933432N21Rik, AI843383, CEP4L, CT79, Gm217, Mtsga10, SPGF26, testis specific 10
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human TSGA10 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • RecF/RecN/SMC N terminal domain
  • chromosome segregation protein SMC, common bacterial type
  • chromosome segregation protein SMC, primarily archaeal type
  • helix-rich Mycoplasma protein
  • protein binding
  • structural molecule

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • spermatogenic failure 16
  • spermatogenic failure 26
role in cell
  • assembly

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • motile cilia
  • sperm fibrous sheath
  • neurites

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human TSGA10 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • spermatogenesis

Cellular Component

Where in the cell the gene product is active
  • motile cilium
  • cytoplasm
  • centriole

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

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