Metrn Gene Summary [Mouse]

Predicted to enable hormone activity. Acts upstream of or within positive regulation of axonogenesis and radial glial cell differentiation. Located in extracellular space. Is expressed in several structures, including eye; genitourinary system; gut; nervous system; and spleen. Orthologous to human METRN (meteorin, glial cell differentiation regulator). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Metrn
Official Name
meteorin, glial cell differentiation regulator [Source:MGI Symbol;Acc:MGI:1917333]
Ensembl ID
ENSMUSG00000002274
Bio databases IDs NCBI: 70083 Ensembl: ENSMUSG00000002274
Aliases meteorin, glial cell differentiation regulator
Synonyms 1810034B16Rik, C16ORF23, c380A1.2, EyeLinc16, Hyrac, Meteorin, meteorin, glial cell differentiation regulator, MGC2601, RGD1306222
Species
Mouse, Mus musculus
OrthologiesHumanRat

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
regulated by
  • decitabine
  • SH-SY5Y cells
  • SP2509
  • TSC2
  • ALK
  • tazemetostat
  • trichostatin A
  • ALOX5
role in cell
  • formation
  • differentiation
  • development

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Extracellular Space

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Metrn gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • positive regulation of axonogenesis
  • signal transduction
  • axonogenesis
  • radial glial cell differentiation
  • glial cell differentiation

Cellular Component

Where in the cell the gene product is active
  • extracellular space

Molecular Function

What the gene product does at the molecular level
  • hormone activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.