Ly6h Gene Summary [Mouse]
Enables acetylcholine receptor binding activity and acetylcholine receptor inhibitor activity. Acts upstream of or within acetylcholine receptor signaling pathway. Predicted to be located in side of membrane and synapse. Predicted to be active in plasma membrane. Is expressed in central nervous system; dorsal root ganglion; and sensory organ. Orthologous to human LY6H (lymphocyte antigen 6 family member H). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Nonsense Mediated Decay |
| Official Symbol | Ly6h |
| Official Name | lymphocyte antigen 6 complex, locus H [Source:MGI Symbol;Acc:MGI:1346030] |
| Ensembl ID | ENSMUSG00000022577 |
| Bio databases IDs | |
| Aliases | lymphocyte antigen 6 complex, locus H |
| Synonyms | lymphocyte antigen 6 family member H, NMLY6 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ly6h often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- acetylcholine receptor inhibitor
- protein binding
- receptor binding
- TFP
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- Extracellular Space
- cellular membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Ly6h gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- nervous system development
- organ morphogenesis
Cellular Component
Where in the cell the gene product is active
- synapse
- extracellular region
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- acetylcholine receptor binding
- acetylcholine receptor inhibitor activity