Zfp592 Gene Summary [Mouse]
Enables PH domain binding activity and insulin receptor substrate binding activity. Acts upstream of or within negative regulation of insulin receptor signaling pathway and regulation of peptidyl-tyrosine phosphorylation. Predicted to be located in nucleus. Is expressed in several structures, including early conceptus; genitourinary system; and neural ectoderm. Orthologous to human ZNF592 (zinc finger protein 592). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Zfp592 |
| Official Name | zinc finger protein 592 [Source:MGI Symbol;Acc:MGI:2443541] |
| Ensembl ID | ENSMUSG00000005621 |
| Bio databases IDs | |
| Aliases | zinc finger protein 592 |
| Synonyms | A730014M16Rik, CAMOS, KIAA0211, SCAR5, Zfp592, zinc finger protein 592 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Zfp592 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- transcription regulator
- zinc-finger C2H2-type
- protein binding
- PH-domain binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Zfp592 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of peptidyl-tyrosine phosphorylation
- regulation of transcription, DNA-dependent
- negative regulation of insulin receptor signaling pathway
Cellular Component
Where in the cell the gene product is active
- nucleus
Molecular Function
What the gene product does at the molecular level
- DNA binding
- sequence-specific DNA binding transcription factor activity
- protein binding
- metal ion binding
- insulin receptor substrate binding
- PH domain binding