ZNF592 Gene Summary [Human]
This gene is thought to play a role in a complex developmental pathway and the regulation of genes involved in cerebellar development. Mutations in this gene have been associated with autosomal recessive spinocerebellar ataxia. [provided by RefSeq, Jan 2011]
Details
| Type | Protein Coding |
| Official Symbol | ZNF592 |
| Official Name | zinc finger protein 592 [Source:HGNC Symbol;Acc:HGNC:28986] |
| Ensembl ID | ENSG00000166716 |
| Bio databases IDs | |
| Aliases | zinc finger protein 592 |
| Synonyms | A730014M16Rik, CAMOS, KIAA0211, SCAR5, Zfp592, zinc finger protein 592 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human ZNF592 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- transcription regulator
- zinc-finger C2H2-type
- protein binding
- PH-domain binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human ZNF592 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of peptidyl-tyrosine phosphorylation
- regulation of transcription, DNA-dependent
- negative regulation of insulin receptor signaling pathway
Cellular Component
Where in the cell the gene product is active
- nucleus
Molecular Function
What the gene product does at the molecular level
- DNA binding
- sequence-specific DNA binding transcription factor activity
- protein binding
- metal ion binding
- insulin receptor substrate binding
- PH domain binding