Prss16 Gene Summary [Mouse]

Predicted to enable dipeptidyl-peptidase activity. Predicted to be involved in proteolysis. Located in endosome and lysosome. Is expressed in epididymis; prostate gland; testis; and thymus. Orthologous to human PRSS16 (serine protease 16). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Prss16
Official Name
protease, serine 16 (thymus) [Source:MGI Symbol;Acc:MGI:1859181]
Ensembl ID
ENSMUSG00000006179
Bio databases IDs NCBI: 54373 Ensembl: ENSMUSG00000006179
Aliases protease, serine 16 (thymus)
Synonyms serine protease 16, serine protease 16 (thymus), TSSP
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Prss16 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • alpha/beta hydrolases
  • peptidase
  • Serine carboxypeptidase S28

Pathways

Biological processes and signaling networks where the Prss16 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • insomnia
  • non-melanoma skin cancer
  • endometriosis
regulated by
  • tetradecanoylphorbol acetate
  • KMT2D
  • PSMB11
  • Gstp1 (includes others)
role in cell
  • abnormal morphology

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Extracellular Space
  • endosomes
  • lysosome

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Prss16 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • protein catabolic process
  • proteolysis

Cellular Component

Where in the cell the gene product is active
  • endosome
  • lysosome

Molecular Function

What the gene product does at the molecular level
  • serine-type peptidase activity
  • dipeptidyl-peptidase activity
  • serine-type exopeptidase activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.