Qrich1 Gene Summary [Mouse]
Predicted to enable DNA binding activity. Involved in response to endoplasmic reticulum stress. Acts upstream of or within kidney development. Predicted to be located in nucleoplasm. Is expressed in several structures, including central nervous system; facial prominence; female reproductive system; spleen; and urinary system. Orthologous to human QRICH1 (glutamine rich 1). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Qrich1 |
| Official Name | glutamine-rich 1 [Source:MGI Symbol;Acc:MGI:1916482] |
| Ensembl ID | ENSMUSG00000006673 |
| Bio databases IDs | |
| Aliases | glutamine-rich 1 |
| Synonyms | 2610028H07Rik, AB-DIP, b2b2404Clo, glutamine-rich 1, RGD1311095, VERBRAS |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Qrich1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Domain of unknown function (DUF3504)
- protein binding
- DNA binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Qrich1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- endoplasmic reticulum unfolded protein response
- positive regulation of transcription, DNA-dependent
- positive regulation of apoptotic process
- intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
- response to endoplasmic reticulum stress
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytoplasm
- plasma membrane
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- DNA binding
- protein binding