Asz1 Gene Summary [Mouse]
Involved in male meiotic nuclear division; spermatogenesis; and transposable element silencing. Located in pi-body. Is expressed in several structures, including central nervous system; genitourinary system; and limb mesenchyme. Orthologous to human ASZ1 (ankyrin repeat, SAM and basic leucine zipper domain containing 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Asz1 |
| Official Name | ankyrin repeat, SAM and basic leucine zipper domain containing 1 [Source:MGI Symbol;Acc:MGI:1921318] |
| Ensembl ID | ENSMUSG00000010796 |
| Bio databases IDs | |
| Aliases | ankyrin repeat, SAM and basic leucine zipper domain containing 1 |
| Synonyms | 4933400N19Rik, ALP1, ANKL1, ankyrin repeat, SAM and basic leucine zipper domain containing 1, C7ORF7, CT1.19, GASZ, ORF3 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Asz1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- transcription regulator
- Ankyrin repeats (many copies)
- SAM (Sterile alpha motif )
- SAM domain (Sterile alpha motif)
- Ankyrin repeats (3 copies)
- protein binding
- Ankyrin repeat
- ankyrin repeats
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- cytoplasmic ribonucleoprotein granule
- Cytoplasm
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Asz1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- negative regulation of transposition, RNA-mediated
- male meiosis
- spermatogenesis
- cell differentiation
- gene silencing by RNA
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- pi-body
Molecular Function
What the gene product does at the molecular level
- protein binding