Bet1 Gene Summary [Mouse]
Predicted to enable SNAP receptor activity and syntaxin binding activity. Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport and vesicle fusion with Golgi apparatus. Predicted to act upstream of or within vesicle-mediated transport. Located in Golgi membrane. Is expressed in cerebral cortex ventricular layer and embryo. Orthologous to human BET1 (Bet1 golgi vesicular membrane trafficking protein). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Bet1 |
| Official Name | Bet1 golgi vesicular membrane trafficking protein [Source:MGI Symbol;Acc:MGI:1343104] |
| Ensembl ID | ENSMUSG00000032757 |
| Bio databases IDs | |
| Aliases | Bet1 golgi vesicular membrane trafficking protein |
| Synonyms | Bet1 golgi vesicular membrane trafficking protein, Golgi vesicular membrane trafficking protein p18, HBET1, MDRP |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Bet1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- cytoplasmic domain
- Helical region found in SNAREs
- protein binding
- SNARE motif
- transporter
- syntaxin binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- endoplasmic reticulum fraction
- Golgi-enriched fraction
- membrane fraction
- Golgi-intermediate compartment membrane fractions
- perinuclear Golgi regions
- cellular membrane
- Golgi Apparatus
- Endoplasmic Reticulum
- ER-to-Golgi intermediate compartment
- cytosol
- endoplasmic reticulum buds
- cis face of the Golgi apparatus
- Golgi membrane
- Golgi buds
- cis Golgi networks
- late endosomes
- peri-Golgi vesicles
- transport vesicles
- microsomal membrane
- Golgi cisternae
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Bet1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- ER to Golgi vesicle-mediated transport
- protein transport
- vesicle fusion with Golgi apparatus
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum membrane
- membrane
- SNARE complex
- Golgi membrane
- transport vesicle
- endoplasmic reticulum-Golgi intermediate compartment membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- SNAP receptor activity