Sh3bp5l Gene Summary [Mouse]

Predicted to enable guanyl-nucleotide exchange factor activity and protein kinase inhibitor activity. Predicted to be involved in intracellular signal transduction. Predicted to be active in cytoplasm. Is expressed in cerebral cortex subventricular zone and cortical plate. Orthologous to human SH3BP5L (SH3 binding domain protein 5 like). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Sh3bp5l
Official Name
SH3 binding domain protein 5 like [Source:MGI Symbol;Acc:MGI:1933124]
Ensembl ID
ENSMUSG00000013646
Bio databases IDs NCBI: 79566 Ensembl: ENSMUSG00000013646
Aliases SH3 binding domain protein 5 like
Synonyms 2310074E09Rik, LOC102555001, mKIAA1720, RGD1307036, SH3 binding domain protein 5 like
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Sh3bp5l often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • SH3 domain-binding protein 5 (SH3BP5)
  • guanyl-nucleotide exchange factor
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • lung cancer
  • systemic sclerosis
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Unknown

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Sh3bp5l gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • intracellular signal transduction

Cellular Component

Where in the cell the gene product is active
  • cytoplasm

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • guanyl-nucleotide exchange factor activity
  • protein kinase inhibitor activity

Gene-Specific Assays for Results You Can Trust

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