Klra17 Gene Summary [Mouse]
Enables MHC class I protein binding activity. Predicted to be active in cell surface. [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Klra17 |
| Official Name | killer cell lectin-like receptor, subfamily A, member 17 [Source:MGI Symbol;Acc:MGI:2180674] |
| Ensembl ID | ENSMUSG00000014543 |
| Bio databases IDs | |
| Aliases | killer cell lectin-like receptor, subfamily A, member 17 |
| Synonyms | killer cell lectin-like receptor, subfamily A, member 17, Ly49q, Ly49q1 |
| Species | Mouse, Mus musculus |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Klra17 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- extracellular domain
- MHC class I protein binding
- C-type lectin (CTL)/C-type lectin-like (CTLD) domain
- immunoreceptor tyrosine-based inhibition motif
- Lectin C-type domain
- Ly49-like protein, N-terminal region
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
- HLA-A
- B2M
- Shp2
- Ptpns1
disease
- plasma cell neoplasm
- B cell cancer
- mature B-cell neoplasia
- infection by Herpesviridae
role in cell
- expression in
- proliferation
- polarization
- number
- production in
- function
- downregulation in
- transmigration
- cell rolling
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cell surface