Tsr3 Gene Summary [Mouse]
Predicted to enable rRNA small subunit aminocarboxypropyltransferase activity. Predicted to be involved in enzyme-directed rRNA pseudouridine synthesis and maturation of SSU-rRNA. Predicted to be located in cytoplasm. Is expressed in forebrain. Orthologous to human TSR3 (TSR3 ribosome maturation factor). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Tsr3 |
| Official Name | TSR3 20S rRNA accumulation [Source:MGI Symbol;Acc:MGI:1915577] |
| Ensembl ID | ENSMUSG00000015126 |
| Bio databases IDs | |
| Aliases | TSR3 20S rRNA accumulation |
| Synonyms | 0610007P22Rik, 1110014B11Rik, C16orf42, HsTsr3, RGD1565744, TSR3 20S rRNA accumulation, TSR3 ribosome maturation factor |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Tsr3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Possible Fer4-like domain in RNase L inhibitor, RLI
- transferase
- enzyme
- Ribosome biogenesis protein, C-terminal
- Non-methyl alkyl or aryl group transferase
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Tsr3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- rRNA modification
- maturation of SSU-rRNA
- enzyme-directed rRNA pseudouridine synthesis
Cellular Component
Where in the cell the gene product is active
- cytosol
Molecular Function
What the gene product does at the molecular level
- transferase activity