Utp25 Gene Summary [Mouse]

Predicted to enable U3 snoRNA binding activity and rRNA binding activity. Involved in positive regulation of embryonic development. Predicted to be part of small-subunit processome. Predicted to be active in nucleolus. Is expressed in cerebral cortex; submandibular gland primordium; tooth; and vibrissa. Orthologous to human UTP25 (UTP25 small subunit processome component). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Utp25
Official Name
UTP25 small subunit processome component [Source:MGI Symbol;Acc:MGI:2138080]
Ensembl ID
ENSMUSG00000016181
Bio databases IDs NCBI: 215193 Ensembl: ENSMUSG00000016181
Aliases UTP25 small subunit processome component
Synonyms C1orf107, DEF, DIEXF, DJ434O14.5, mDef, UTP25 small subunit processome component
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Utp25 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Utp25, U3 small nucleolar RNA-associated SSU processome protein 25
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • nucleoplasm
  • nucleoli

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Utp25 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • protein destabilization
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • protein catabolic process
  • embryonic organ development
  • positive regulation of embryonic development

Cellular Component

Where in the cell the gene product is active
  • small-subunit processome
  • nucleolus
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • RNA binding
  • U3 snoRNA binding
  • rRNA binding

Gene-Specific Assays for Results You Can Trust

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