Rps9 Gene Summary [Mouse]
A structural constituent of ribosome. Predicted to be involved in positive regulation of cell population proliferation; ribosomal small subunit biogenesis; and translation. Part of cytosolic small ribosomal subunit. Is active in synapse. Is expressed in several structures, including cerebral cortex; diaphragm; eye; genitourinary system; and soleus. Orthologous to human RPS9 (ribosomal protein S9). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Rps9 |
| Official Name | ribosomal protein S9 [Source:MGI Symbol;Acc:MGI:1924096] |
| Ensembl ID | ENSMUSG00000006333 |
| Bio databases IDs | |
| Aliases | ribosomal protein S9 |
| Synonyms | 3010033P07RIK, AC012314.14, AC012314.15, AC012314.17, AC012314.3, AC012314.6, AC012314.7, LOC100909466, Ribo s9, ribosomal protein S9, Rps9l1, S9, uS4 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Rps9 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- ribosomal protein uS4, eukaryotic/archaeal type
- structural constituent of ribosome
- S4
- rRNA binding
- S4 domain
- protein binding
- Ribosomal protein S4/S9 N-terminal domain
- translation regulator
Pathways
Biological processes and signaling networks where the Rps9 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- Crohn disease
- Takayasu arteritis
regulates
- TP53
- DNA endogenous promoter
- CDK1
- RNR
- RPS
role in cell
- proliferation
- growth
- cell cycle progression
- downregulation in
- translation in
- processing in
- homologous recombination in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- interchromatin granule cluster fractions
- pre-ribosome
- ribosome
- Nucleus
- cytosol
- granular components
- nucleoplasm
- nucleoli
- synapse
- cytosolic fraction
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Rps9 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of translation
- cytoplasmic translation
- positive regulation of cell proliferation
- ribosomal small subunit biogenesis
- translation
Cellular Component
Where in the cell the gene product is active
- small-subunit processome
- cytosolic ribosome
- cytosolic small ribosomal subunit
- synapse
- nucleolus
- ribosome
- nucleoplasm
- nucleus
- extracellular vesicular exosome
- focal adhesion
- cytoplasm
- membrane
- cytosol
Molecular Function
What the gene product does at the molecular level
- translation regulator activity
- RNA binding
- protein binding
- structural constituent of ribosome
- rRNA binding