Cox7c Gene Summary [Mouse]
Predicted to be involved in mitochondrial electron transport, cytochrome c to oxygen. Located in mitochondrion. Part of respiratory chain complex IV. Is active in mitochondrial inner membrane. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Orthologous to human COX7C (cytochrome c oxidase subunit 7C). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Cox7c |
| Official Name | cytochrome c oxidase subunit 7C [Source:MGI Symbol;Acc:MGI:103226] |
| Ensembl ID | ENSMUSG00000017778 |
| Bio databases IDs | |
| Aliases | cytochrome c oxidase subunit 7C |
| Synonyms | AI648091, Cox7c1, COXVIIc, cytochrome c oxidase subunit 7C |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Cox7c often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- cytochrome-c oxidase
- Cyt_c_Oxidase_VIIc
- enzyme
- protein binding
Pathways
Biological processes and signaling networks where the Cox7c gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- metabolic syndrome X
- chronic obstructive pulmonary disease
- Huntington disease
- peripheral arterial disease
- chronic kidney disease
- insulin resistance
regulates
- COX7C
- cytochrome-c oxidase
role in cell
- expression in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria
- mitochondrial membrane
- mitochondrial inner membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Cox7c gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- generation of precursor metabolites and energy
- mitochondrial electron transport, cytochrome c to oxygen
- cellular respiration
Cellular Component
Where in the cell the gene product is active
- mitochondrial membrane
- mitochondrion
- mitochondrial respiratory chain complex IV
- mitochondrial inner membrane
Molecular Function
What the gene product does at the molecular level
- protein binding