Jrk Gene Summary [Mouse]
Enables mRNA binding activity. Predicted to be involved in positive regulation of canonical Wnt signaling pathway. Located in cytoplasm and nucleus. Part of ribonucleoprotein complex. Is expressed in several structures, including central nervous system; early conceptus; eye; and genitourinary system. Orthologous to human JRK (Jrk helix-turn-helix protein). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Jrk |
| Official Name | jerky [Source:MGI Symbol;Acc:MGI:106214] |
| Ensembl ID | ENSMUSG00000046380 |
| Bio databases IDs | |
| Aliases | jerky |
| Synonyms | Jerky, JH8, Jrk helix-turn-helix protein |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Jrk often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- DDE superfamily endonuclease
- mRNA binding
- Tc5 transposase DNA-binding domain
- protein binding
- HTH_CRP
- CENP-B N-terminal DNA-binding domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- Cytoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Jrk gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- positive regulation of canonical Wnt receptor signaling pathway
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytoplasm
Molecular Function
What the gene product does at the molecular level
- DNA binding
- protein binding
- mRNA binding