Slc25a39 Gene Summary [Mouse]

Predicted to enable 2 iron, 2 sulfur cluster binding activity and glutathione transmembrane transporter activity. Predicted to be involved in cellular response to iron ion and glutathione import into mitochondrion. Located in mitochondrion. Is expressed in several structures, including alimentary system; extraembryonic component; liver; nervous system; and skeleton. Orthologous to human SLC25A39 (solute carrier family 25 member 39). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Slc25a39
Official Name
solute carrier family 25, member 39 [Source:MGI Symbol;Acc:MGI:1196386]
Ensembl ID
ENSMUSG00000018677
Bio databases IDs NCBI: 68066 Ensembl: ENSMUSG00000018677
Aliases solute carrier family 25, member 39
Synonyms 3010027G13Rik, CGI-69, D11Ertd333e, RGD1306193, solute carrier family 25 member 39, solute carrier family 25, member 39
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Slc25a39 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • binding protein
  • Mitochondrial carrier protein
  • organic anion transporter
  • tripeptide transporter
  • transporter

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • chronic obstructive pulmonary disease
regulated by
role in cell
  • growth
  • response by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Mitochondria
  • mitochondrial inner membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Slc25a39 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • heme biosynthetic process
  • cellular response to iron ion
  • transport

Cellular Component

Where in the cell the gene product is active
  • mitochondrion
  • mitochondrial inner membrane

Molecular Function

What the gene product does at the molecular level
  • metal ion binding
  • 2 iron, 2 sulfur cluster binding
  • glutathione transmembrane transporter activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.