Sntg2 Gene Summary [Mouse]
Predicted to enable PDZ domain binding activity and neuroligin family protein binding activity. Predicted to be located in nucleoplasm and plasma membrane. Predicted to be part of dystrophin-associated glycoprotein complex. Is expressed in gut and urinary system. Orthologous to human SNTG2 (syntrophin gamma 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Nonsense Mediated Decay |
| Official Symbol | Sntg2 |
| Official Name | syntrophin, gamma 2 [Source:MGI Symbol;Acc:MGI:1919541] |
| Ensembl ID | ENSMUSG00000020672 |
| Bio databases IDs | |
| Aliases | syntrophin, gamma 2 |
| Synonyms | 2210008K22Rik, 9530013L23, G2SYN, SYN5, syntrophin gamma 2, syntrophin, gamma 2, syntrophin γ 2, syntrophin, γ 2 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Sntg2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Domain present in PSD-95, Dlg, and ZO-1/2
- canonical PDZ domain
- protein binding
- receptor binding
- PDZ domain
- PDZ-domain binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cellular membrane
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Sntg2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- central nervous system development
Cellular Component
Where in the cell the gene product is active
- cytoskeleton
- cytoplasm
- sarcolemma
- dystrophin-associated glycoprotein complex
- syntrophin complex
- intracellular
- plasma membrane
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- actin binding
- PDZ domain binding
- structural molecule activity
- neuroligin family protein binding