Drp2 Gene Summary [Mouse]
Predicted to enable zinc ion binding activity. Predicted to be involved in synapse organization and synaptic signaling. Located in plasma membrane. Is expressed in several structures, including adrenal gland; alimentary system; brain; genitourinary system; and hemolymphoid system gland. Orthologous to human DRP2 (dystrophin related protein 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Drp2 |
| Official Name | dystrophin related protein 2 [Source:MGI Symbol;Acc:MGI:107432] |
| Ensembl ID | ENSMUSG00000000223 |
| Bio databases IDs | |
| Aliases | dystrophin related protein 2 |
| Synonyms | dystrophin related protein 2 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Drp2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- EF-Hand
- SPEC
- ZZ
- Spectrin repeats
- Domain with 2 conserved Trp (W) residues
- EF hand
- WW
- EF-hand-like motif found in the dystrophin/dystrobrevin/dystrotelin family
- Spectrin repeat
- coiled-coil domain
- protein binding
- WW domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- glutaminergic synapse
- cytosol
- dendrites
- postsynaptic density
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Drp2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- central nervous system development
- synapse organization
Cellular Component
Where in the cell the gene product is active
- dendrite
- postsynaptic density
- perikaryon
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- zinc ion binding