Dtd2 Gene Summary [Mouse]

Enables Ala-tRNA(Thr) deacylase activity and D-tyrosyl-tRNA(Tyr) deacylase activity. Involved in aminoacyl-tRNA metabolism involved in translational fidelity. Predicted to be active in cytoplasm. Orthologous to human DTD2 (D-aminoacyl-tRNA deacylase 2). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Dtd2
Official Name
D-tyrosyl-tRNA deacylase 2 [Source:MGI Symbol;Acc:MGI:1923485]
Ensembl ID
ENSMUSG00000020956
Bio databases IDs NCBI: 328092 Ensembl: ENSMUSG00000020956
Aliases D-tyrosyl-tRNA deacylase 2
Synonyms 4930578F06RIK, 6530401N04Rik, ATD, B830049N13Rik, C14orf126, D-aminoacyl-tRNA deacylase 2, D-tyrosyl-tRNA deacylase 2, LOC638977, RGD1309138
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Dtd2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • carboxylic ester hydrolase
  • D-Tyr-tRNA(Tyr) deacylase
  • Dtyr_deacylase
  • enzyme
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
role in cell
  • apoptosis

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Unknown

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Dtd2 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • tRNA metabolic process

Cellular Component

Where in the cell the gene product is active
  • cytoplasm

Molecular Function

What the gene product does at the molecular level
  • D-tyrosyl-tRNA(Tyr) deacylase activity
  • protein binding
  • tRNA binding