Comtd1 Gene Summary [Mouse]
Predicted to enable S-adenosylmethionine-dependent methyltransferase activity. Predicted to be involved in methylation. Located in mitochondrion. Is expressed in alimentary system; liver; and nervous system. Orthologous to human COMTD1 (catechol-O-methyltransferase domain containing 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Comtd1 |
| Official Name | catechol-O-methyltransferase domain containing 1 [Source:MGI Symbol;Acc:MGI:1916406] |
| Ensembl ID | ENSMUSG00000021773 |
| Bio databases IDs | |
| Aliases | catechol-O-methyltransferase domain containing 1 |
| Synonyms | 1810030M08Rik, catechol-O-methyltransferase domain containing 1, MT773 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Comtd1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- O-methyltransferase
- enzyme
- protein binding
- AdoMet_MTases
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cellular membrane
- Mitochondria
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Comtd1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- methylation
Cellular Component
Where in the cell the gene product is active
- membrane
Molecular Function
What the gene product does at the molecular level
- O-methyltransferase activity
- protein binding
- S-adenosylmethionine-dependent methyltransferase activity