Prm1 Gene Summary [Mouse]

Predicted to enable DNA binding activity. Acts upstream of or within nucleus organization and spermatid development. Located in male germ cell nucleus. Is expressed in testis. Orthologous to human PRM1 (protamine 1). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Prm1
Official Name
protamine 1 [Source:MGI Symbol;Acc:MGI:97765]
Ensembl ID
ENSMUSG00000022501
Bio databases IDs NCBI: 19118 Ensembl: ENSMUSG00000022501
Aliases protamine 1
Synonyms CT94.1, P1, protamine 1
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Prm1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • arginine serine dipeptide repeat domain
  • protein binding
  • DNA binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • teratozoospermia
  • infertility condition
regulates
role in cell
  • organization
  • development
  • condensation

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • nuclear fraction
  • cytosol
  • nucleoplasm
  • sperm head

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Prm1 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • chromosome organization
  • spermatogenesis
  • chromosome condensation
  • sperm chromatin condensation

Cellular Component

Where in the cell the gene product is active
  • cytosol
  • nucleosome
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • DNA binding
  • protein binding

Gene-Specific Assays for Results You Can Trust

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