PRM1 Gene Summary [Human]
Predicted to enable DNA binding activity. Predicted to be involved in DNA packaging. Predicted to act upstream of or within nucleus organization and spermatid development. Located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | PRM1 |
| Official Name | protamine 1 [Source:HGNC Symbol;Acc:HGNC:9447] |
| Ensembl ID | ENSG00000175646 |
| Bio databases IDs | |
| Aliases | protamine 1, cancer/testis antigen family 94, member 1 |
| Synonyms | CT94.1, P1, protamine 1 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human PRM1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- arginine serine dipeptide repeat domain
- protein binding
- DNA binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nuclear fraction
- cytosol
- nucleoplasm
- sperm head
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human PRM1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- chromosome organization
- spermatogenesis
- chromosome condensation
- sperm chromatin condensation
Cellular Component
Where in the cell the gene product is active
- cytosol
- nucleosome
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- DNA binding
- protein binding