Strbp Gene Summary [Mouse]
Enables double-stranded RNA binding activity; microtubule binding activity; and single-stranded RNA binding activity. Acts upstream of or within cell motility; mechanosensory behavior; and spermatid development. Located in manchette. Is expressed in central nervous system; dorsal root ganglion; metanephros; sensory organ; and trigeminal nerve. Orthologous to human STRBP (spermatid perinuclear RNA binding protein). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Nonsense Mediated Decay |
| Official Symbol | Strbp |
| Official Name | spermatid perinuclear RNA binding protein [Source:MGI Symbol;Acc:MGI:104626] |
| Ensembl ID | ENSMUSG00000026915 |
| Bio databases IDs | |
| Aliases | spermatid perinuclear RNA binding protein |
| Synonyms | 6430510M02RIK, C230082I21RIK, HEL162, ILF3L, p74, spermatid perinuclear RNA binding protein, SPNR |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Strbp often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- DZF domain
- microtubule binding
- Double-stranded RNA binding motif
- tubulin binding
- double-stranded RNA binding motif (DSRM) superfamily
- double-stranded RNA binding
- protein binding
- dsRNA-binding domain
- single-stranded RNA binding
Pathways
Biological processes and signaling networks where the Strbp gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- microtubule cytoskeleton
- manchette
- Nucleus
- microtubules
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Strbp gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- mechanosensory behavior
- cell motility
- spermatid development
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytoplasm
- manchette
Molecular Function
What the gene product does at the molecular level
- DNA binding
- RNA binding
- protein binding
- double-stranded RNA binding
- single-stranded RNA binding
- microtubule binding