Osbpl11 Gene Summary [Mouse]
Predicted to enable sterol binding activity. Predicted to be involved in fat cell differentiation and positive regulation of triglyceride storage. Predicted to be located in nucleoplasm. Predicted to be active in Golgi apparatus; cytosol; and membrane. Is expressed in several structures, including central nervous system; genitourinary system; heart; immune system; and lung. Orthologous to human OSBPL11 (oxysterol binding protein like 11). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Osbpl11 |
| Official Name | oxysterol binding protein-like 11 [Source:MGI Symbol;Acc:MGI:2146553] |
| Ensembl ID | ENSMUSG00000022807 |
| Bio databases IDs | |
| Aliases | oxysterol binding protein-like 11 |
| Synonyms | 9430097N02Rik, AI132306, ORP-11, OSBP12, oxysterol binding protein-like 11, TCCCIA00292 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Osbpl11 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- PH domain
- protein binding
- Pleckstrin homology-like domain
- Oxysterol-binding protein
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Nucleus
- Golgi Apparatus
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Osbpl11 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- lipid transport
- positive regulation of sequestering of triglyceride
- fat cell differentiation
Cellular Component
Where in the cell the gene product is active
- late endosome membrane
- membrane
- cytosol
- Golgi apparatus
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- sterol binding
- protein binding