Ece2

Predicted to enable metalloendopeptidase activity. Predicted to be involved in protein processing. Predicted to act upstream of or within peptide hormone processing. Predicted to be located in Golgi membrane; trans-Golgi network; and transport vesicle membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including adrenal gland; genitourinary system; gut; heart; and nervous system. Orthologous to human ECE2 (endothelin converting enzyme 2). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ece2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Ece2 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.