Nckap5l Gene Summary [Mouse]

Predicted to be involved in microtubule bundle formation and microtubule depolymerization. Predicted to be located in centrosome. Predicted to be active in microtubule plus-end. Is expressed in central nervous system and retina. Orthologous to human NCKAP5L (NCK associated protein 5 like). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Nckap5l
Official Name
NCK-associated protein 5-like [Source:MGI Symbol;Acc:MGI:3609653]
Ensembl ID
ENSMUSG00000023009
Bio databases IDs NCBI: 380969 Ensembl: ENSMUSG00000023009
Aliases NCK-associated protein 5-like
Synonyms C230021P08Rik, Cep169, FP1193, KIAA1602, LOC100912824, LOC283331, NCK-associated protein 5-like, RGD1561571
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Nckap5l often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • ZIP_TSC22D-like
  • protein binding
  • Nck-associated protein 5, Peripheral clock protein

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
role in cell
  • formation
  • depolymerization

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • centrosome
  • microtubules

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Nckap5l gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • microtubule bundle formation
  • microtubule depolymerization

Cellular Component

Where in the cell the gene product is active
  • centrosome
  • cytoplasm
  • microtubule plus end

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

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