Zscan10 Gene Summary [Mouse]

Enables DNA-binding transcription factor activity and sequence-specific DNA binding activity. Involved in negative regulation of DNA-templated transcription. Located in nucleus. Is expressed in several structures, including early conceptus; genitourinary system; gut; limb mesenchyme; and nervous system. Orthologous to human ZSCAN10 (zinc finger and SCAN domain containing 10). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Zscan10
Official Name
zinc finger and SCAN domain containing 10 [Source:MGI Symbol;Acc:MGI:3040700]
Ensembl ID
ENSMUSG00000023902
Bio databases IDs NCBI: 332221 Ensembl: ENSMUSG00000023902
Aliases zinc finger and SCAN domain containing 10
Synonyms OFNS, ZFP206, zinc finger and SCAN domain containing 10, Zkscan10, ZNF206
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Zscan10 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Zinc finger, C2H2 type
  • leucine rich region
  • transcription regulator
  • Zinc-finger double domain
  • SCAN domain
  • protein binding
  • sequence-specific DNA binding
  • transcription factor activity

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
disease
  • otofacial neurodevelopmental syndrome
regulated by
regulates
role in cell
  • expression in
  • differentiation

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • nucleoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Zscan10 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • negative regulation of transcription, DNA-dependent
  • regulation of transcription from RNA polymerase II promoter

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • sequence-specific DNA binding transcription factor activity
  • protein binding
  • metal ion binding
  • RNA polymerase II core promoter proximal region sequence-specific DNA binding
  • sequence-specific DNA binding
  • sequence-specific DNA binding RNA polymerase II transcription factor activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.