Tekt4 Gene Summary [Mouse]

Involved in flagellated sperm motility. Acts upstream of with a positive effect on regulation of brood size. Acts upstream of or within cilium movement involved in cell motility. Located in sperm midpiece and sperm principal piece. Is active in axonemal A tubule inner sheath and sperm flagellum. Is expressed in choroid invagination; diencephalon roof plate; and metencephalon part of 4th ventricle choroid plexus. Orthologous to human TEKT4 (tektin 4). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Processed Transcript
Official Symbol
Tekt4
Official Name
tektin 4 [Source:MGI Symbol;Acc:MGI:1919090]
Ensembl ID
ENSMUSG00000024175
Bio databases IDs NCBI: 71840 Ensembl: ENSMUSG00000024175
Aliases tektin 4
Synonyms 1700010L19Rik, RGD1308075, Tek4, Tektin4
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Tekt4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • protein binding
  • Tektin family
  • transporter

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • asthenozoospermia
regulates
  • adenosine triphosphate
role in cell
  • abnormal morphology
  • function
  • morphology
  • motility

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • flagella
  • axonemes
  • sperm midpiece
  • sperm tail

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Tekt4 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • cilium morphogenesis
  • cilium movement involved in cell motility

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • axonemal microtubule
  • microtubule cytoskeleton
  • sperm flagellum

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

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