Pgap6 Gene Summary [Mouse]
Predicted to enable phospholipase A2 activity. Predicted to be involved in lipid metabolic process. Predicted to be located in plasma membrane. Is expressed in several structures, including cranial ganglion; epiblast; genitourinary system; gut; and olfactory epithelium. Orthologous to human PGAP6 (post-GPI attachment to proteins 6). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Pgap6 |
| Official Name | post-glycosylphosphatidylinositol attachment to proteins 6 [Source:MGI Symbol;Acc:MGI:1926283] |
| Ensembl ID | ENSMUSG00000024180 |
| Bio databases IDs | |
| Aliases | post-glycosylphosphatidylinositol attachment to proteins 6 |
| Synonyms | GPI-PLA2, LOC105371036, M83, post-glycosylphosphatidylinositol attachment to proteins 6, post-GPI attachment to proteins 6, Rxylt1, TMEM6, TMEM8, TMEM8A |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Pgap6 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Protein of unknown function (DUF3522)
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cell surface
- cellular membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Pgap6 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- lipid metabolic process
Cellular Component
Where in the cell the gene product is active
- extracellular vesicular exosome
- lysosomal membrane
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- phospholipase A2 activity
- protein binding